Msp1: patrolling mitochondria for lost proteins.
نویسنده
چکیده
Intracellular protein localization is critical for establishing organelle identity, avoiding inappropriate interactions, and maintaining cellular function. An emerging mechanism for ensuring high-fidelity protein localization is the selective destruction of mislocalized copies. Two new papers find that the mitochondrial outer membrane is kept free of mislocalized proteins by Msp1 (Chen et al, 2014; Okreglak & Walter, 2014).
منابع مشابه
The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane
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ورودعنوان ژورنال:
- The EMBO journal
دوره 33 14 شماره
صفحات -
تاریخ انتشار 2014